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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
Postnatal

5 matching records from 5 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pcsk5  proprotein convertase subtilisin/kexin type 5   (Synonyms: b2b1549Clo, b2b585Clo, PC5/6A, PC5A, PC6, SPC6)
Results  Reference
1*J:34068 Constam DB, Calfon M, Robertson EJ, SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91
1*J:104195 Essalmani R, Hamelin J, Marcinkiewicz J, Chamberland A, Mbikay M, Chretien M, Seidah NG, Prat A, Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse. Mol Cell Biol. 2006 Jan;26(1):354-61
1J:134264 Essalmani R, Zaid A, Marcinkiewicz J, Chamberland A, Pasquato A, Seidah NG, Prat A, In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5750-5
1J:174826 Rousselet E, Marcinkiewicz J, Kriz J, Zhou A, Hatten ME, Prat A, Seidah NG, PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
1J:79640 Wong BS, Liu S, Schultz GA, Rancourt DE, Subtilisin proprotein convertase-6 expression in the mouse uterus during implantation and artificially induced decidualization. Mol Reprod Dev. 2002 Apr;61(4):453-9

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory